Characterization and analysis of the antidiabetic activities of sulphated polysaccharide extract from Caulerpa lentillifera

Caulerpa lentillifera is a type of green seaweed that cultivated in tropical and subtropical areas. The objectives this study were to determine the characteristics sulfated polysaccharides from C. evaluate its antidiabetic activity. In initial process study, samples macerated with ethanol (1:10). Then, maceration residue was extracted an accumulator at 75 °C for three hours. crude extract yield 4.16% based on weight seaweed. Ion chromatography purification DEAE-Sepharose resin provided 14.8% extract. monomer analysis purified revealed galactose monomers dominant glucose minor component. total carbohydrate sulfate contents higher than those . Bioactivity tests had activity against α-glucosidase enzyme ones IC 50 values 134.81± 2.0 µg/mL. Purified could potentially be used as medication.